朱海涛;刘哲豪;
ZHU Haitao;LIU Zhehao;Department of Hepatobiliary Surgery,the Affilated Hospital of Guizhou Medical University;

• 1:贵州医科大学附院肝胆外科

摘要(Abstract)：

目的:观察急性胰腺炎(AP)的标准治疗方法联合生大黄灌肠对胆源性、高脂血症性及特发性轻症AP的治疗效果。方法:74例轻症AP患者,根据病因分为胆源性、高脂血症性及特发性3类,再根据治疗方法分为标准治疗组(采用标准治疗)和联合治疗组(采用标准治疗联合生大黄灌肠治疗),比较各组AP患者腹痛缓解时间、腹部压痛缓解时间、排气时间,同时观察各组AP患者血淀粉酶、白细胞及血糖恢复正常时间。结果:联合治疗组3类轻症AP患者腹痛缓解时间、腹部压痛缓解时间及排气时间短于标准治疗组患者,差异有统计学意义(P<0.05);但两种治疗方法的3类轻症AP患者血糖恢复正常时间比较,差异无统计学意义(P>0.05);联合治疗组胆源性和特发性轻症AP患者白细胞恢复正常时间优于标准治疗组,差异有统计学意义(P<0.05);联合治疗组胆源性和高脂血症型轻症AP患者血淀粉酶恢复正常时间优于标准治疗组,差异有统计学意义(P<0.05)。结论:标准治疗联合生大黄灌肠治疗胆源性、高脂血症性、特发性轻症AP可缩短患者腹痛、腹部压痛缓解时间及排气时间,对患者血糖恢复正常时间无影响;对高脂血症性轻症AP白细胞恢复正常时间和特发性轻症AP血淀粉酶恢复正常时间无影响。
Objective: To observe the therapeutic effect of standard treatment combined with rhubarb enema in treating biliary,hyperlipidemia and idiopathic mild acute pancreatitis( AP). Methods: 74 patients with mild AP were divided into biliary,hyperlipidemia and idiopathic AP according to different causes,and were randomly divided into standard treatment group and standard treatment group combined rhubarb enema group. Remission time of abdominal pain,abdominal tenderness relief time,exhaust time were compared between each group. Recovery time of blood amylase,white blood cell and blood glucose were observed. Results: Remission time of abdominal pain,abdominal tenderness relief time,exhaust time of patients with 3 type mild AP in combined treatment group were shorter than those in standard treatment group,and the difference was statistically significant( P < 0. 05). But the difference of blood glucose recovery time between the two groups were not statistically significant( P >0. 05). The leukocyte recovery time of patients with biliary or idiopathic mild AP in combined treatment group were shorter than those in standard treatment group,and the difference was statistically significant( P < 0. 05). Recovery time of blood amylase of patients with biliary or hyperlipidemia mild AP in combined treatment group were shorter than those in standard treatment group,and the difference was statistically significant( P < 0. 05). Conclusions: Standard treatment combined with rhubarb enema in treating mild AP with can shorten remission time of abdominal pain,abdominal tenderness relief time,exhaust time.

关键词(KeyWords)： 急性胰腺炎;胆源性;高脂血症性;特发性;生大黄;灌肠;前瞻性队列研究;疗效
acute pancreatitis;biliary;hyperlipidemia;idiopathic;rhubarb;enema;prospective cohort study;curative efficacy

Abstract:

Keywords:

基金项目(Foundation): 贵州省科技计划项目[黔科合LH字(2016)7232号,黔科合J字(2014)2015号];; 贵阳医学院附属医院博士启动基金

作者(Author): 朱海涛;刘哲豪;
ZHU Haitao;LIU Zhehao;Department of Hepatobiliary Surgery,the Affilated Hospital of Guizhou Medical University;

Email:

DOI: 10.19367/j.cnki.1000-2707.2017.11.016

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