贵州医科大学学报

2016, v.41;No.190(07) 855-857+861

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黔东南州育龄夫妇地中海贫血筛查
Screening on Thalassemia Couples of Reproductive Age in Qian Dongnan Area

孔义华;戴志敏;刘杰麟;龙纯意;吴秋阳;梅艳;
KONG Yihua;DAI Zhimin;LIU Jielin;LONG Chunyi;WU Qiuyang;MEI Yan;Second Affiliated Hospital of Guizhou Medical University;Stem Cell Research Center,Guizhou Medical University;

摘要(Abstract):

目的:了解贵州省黔东南州地区部分育龄夫妇地中海贫血发生率。方法:采用血细胞分析和血红蛋白电泳对黔东南州部分地区1 516对育龄夫妇进行地中海贫血筛查,比较不同性别不同民族孕龄夫妇地中海贫血筛查阳性率。结果:1 516对育龄夫妇(共3 032人)中,血细胞分析有279例地中海贫血筛查阳性,阳性率为9.2%;血红蛋白电泳显示617例地中海贫血筛查阳性,阳性率20.3%;女性地中海贫血筛查阳性率高于男性(P<0.05),苗族与侗族地中海贫血阳性率高于汉族,侗族与壮族地中海贫血阳性率高于水族(P<0.05)。结论:黔东南州不同性别,不同民族间地中海贫血筛查阳性率差别较大。
Objective: To investigate incidence rate of thalassemia in couples of reproductive age in Qian Dongnan Area of Guizhou Province. Methods: Adopting the blood cell analysis and the hemoglobin electrophoresis to screen Qian Dongnan Area 1 516 couples of thalassemia,comparing positive rate of couples of different gender and minority groups. Results: The results of 3 032 cases of participants showed 279 cases blood cell were tested as positive,positive rate is 9. 2%; Hemoglobin electrophoresis showed 617 positive cases,positive rate is 20. 3%; female thalassemia screen rate was higher than that of male( P < 0. 05). Thalassemia positive rate of Miao and Dong people were higher than that of Han people,Thalassemia positive rate of Dong and Zhuang people were higher than that of Shui people( P< 0. 05). Conclusion: Thalassemia screen rate varies among people from different ethnic group of Qiandongnan.

关键词(KeyWords): 地中海贫血;贵州;血细胞分析;血红蛋白电泳
thalassemia;Guizhou;blood cell ananlysis;hemoglobin electrophoresis

Abstract:

Keywords:

基金项目(Foundation): 黔东南州科技项目[黔东南科合J字(2014)4031]

作者(Author): 孔义华;戴志敏;刘杰麟;龙纯意;吴秋阳;梅艳;
KONG Yihua;DAI Zhimin;LIU Jielin;LONG Chunyi;WU Qiuyang;MEI Yan;Second Affiliated Hospital of Guizhou Medical University;Stem Cell Research Center,Guizhou Medical University;

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DOI: 10.19367/j.cnki.1000-2707.2016.07.028

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