贵州医科大学学报

2004, (06) 502-504

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结直肠腺瘤患者术后血脂、脂蛋白、血钙及维生素C水平检测
The Monitoring on Contents of Blood Lipids and Lipoproteins, Blood Calcium and Vitamin C of Patients with Colorectal Adenoma after Operation

杨卫文,杨景林,黎莉,王亚菲,陈薇
YANG Wei wen, YANG Jing lin, LI Li, WANG Ya fei, CHEN Wei (Department of Digestive Internal Medicine, The Second People’s Hospital of Guiyang, Guiyang 550005, China)

摘要(Abstract):

目的 :探讨血脂、脂蛋白、血钙及维生素C水平在结直肠腺瘤术后患者随访中的价值。方法 :结直肠腺瘤患者 118例 ,随机分成治疗组 70例 ,对照组 4 8例。治疗组在腺瘤摘除前测定血脂及脂蛋白、血钙、维生素C水平 ,摘除后给予低脂饮食、补钙及维生素C ,在摘除后 3月、6月及 1年作肠镜随访 ,同时测定上述各指标 ;对照组腺瘤摘除后未作任何治疗 ,仅作肠镜随访。结果 :(1)腺瘤摘除后 3月、6月及 1年 ,治疗组的复发率低于对照组 ,总复发率显著降低 (P <0 0 5 ) ;(2 )治疗组从腺瘤摘除后 3月开始血TC、TG、LDL C水平显著下降 ,HDL C、血钙、维生素C水平显著升高 ,摘除后 1年复发患者血TC、TG水平较未复发患者显著升高 ,维生素C水平显著下降 ,达摘除前水平 ,而HDL C、LDL C、血钙水平无显著变化。结论 :低脂饮食、补钙及维生素C有预防腺瘤复发的作用 ,监测血TC、TG及维生素C水平可以帮助了解腺瘤复发情况。
Objective: To explore the value of monitoring on the blood lipids and lipoproteins, blood calcium, and vitamin C in patients with colorectal adenoma in the long term follow up visit. Methods: 118 patients with colorectal adenoma were divided into cured group and control group at random. The contents of blood lipids and lipoproteins, blood calcium, and vitamin C of the cured group were measured before the adenoma resection, and then, the patients were given food with low lipid and enriched calcium and vitamin C. The contents of the above elements were tested and enteroscopy was carried out for the patients in 3, 6, and 12 months after the operation. Patients in the control group were not given special treatment but regular visit after the adenoma resection. Results: 1) The recurrence rate of the cured group declined greatly. 2) The levels of TC, TG, LDL C of the cured group declined greatly 3 months after the adenoma resection, and the levels of HDL C, blood calcium, vitamin C rose greatly. The levels of blood TC, TG in patients of the recurring group were much higher and the level of vitamin C was much lower than the non recurring group and the levels of HDL C, LDL C and blood calcium did not change in one year after the operation. Conclusions: The diet with low lipid, enriched calcium and vitamin C benefit patients in decline the recurrence of adenoma. To test the levels of blood TC, TG and vitamin C could help monitoring the recurrence. [

关键词(KeyWords): 结直肠肿瘤;脂蛋白类;钙;抗坏血酸;血浆
colorectal neoplasms; lipoproteins; calcium; ascorbic acid; plasma

Abstract:

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作者(Author): 杨卫文,杨景林,黎莉,王亚菲,陈薇
YANG Wei wen, YANG Jing lin, LI Li, WANG Ya fei, CHEN Wei (Department of Digestive Internal Medicine, The Second People’s Hospital of Guiyang, Guiyang 550005, China)

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DOI: 10.19367/j.cnki.1000-2707.2004.06.012

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