蒋宪瑶,龙曼海,张爱华,吴应宽,罗鹏,邱燕
JIANG Xian yao 1, LONG Man hai 1, ZHANG Ai hua 1, WU Ying kuan 1, LUO Peng 1, QIU Yan 2 (1.School of Public Health, Guiyang Medical College, Guiyang 550004, China; 2. The Central Station of Environmental Monitoring, Nantong 226000, Jiangsu, China)

• 1:贵阳医学院预防医学系
• 2:贵阳医学院预防医学系
• 3:贵阳医学院预防医学系
• 4:贵阳医学院预防医学系

摘要(Abstract)：

目的 :研究新型农药多噻烷有无迟发神经毒性。方法 :按农药登记毒理学试验方法 (GB15 6 70 1995 )进行试验。结果 :多噻烷对动物体重有影响但无任何迟发神经毒性症状 ,病理组织学检查神经系统各部位均无组织坏死及炎症变化。结论 :多噻烷无迟发神经毒性作用。
Objective: To study the delayed neurotoxicity after acute poisoning of PCTA in female chickens. Methods: The toxicological test methods for pesticides registration (GB15670 1995) were used. Results: PCTA showed effect on body weight of female chickens, but no symptom of delayed neurotoxicity was observed. The pathological examination showed no necrosis or inflammation in the whole neural system. Conclusion: PCTA has no delayed neurotoxicity effect. [

关键词(KeyWords)： 多噻烷;神经变性;组织学
Polythiacycaoalkanes; nerve degeneration; histology

Abstract:

Keywords:

基金项目(Foundation):

作者(Author): 蒋宪瑶,龙曼海,张爱华,吴应宽,罗鹏,邱燕
JIANG Xian yao 1, LONG Man hai 1, ZHANG Ai hua 1, WU Ying kuan 1, LUO Peng 1, QIU Yan 2 (1.School of Public Health, Guiyang Medical College, Guiyang 550004, China; 2. The Central Station of Environmental Monitoring, Nantong 226000, Jiangsu, China)

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DOI: 10.19367/j.cnki.1000-2707.2004.06.015

参考文献(References)：

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• [2]朱延韦,蒋宪瑶,蒙顺松,等.贵州省沙蚕毒系新农药-多噻烷毒性研究[J].职业卫生与病伤,1987,2(1):22-25.
• [3]朱延韦,蒋宪瑶,张爱华,等.多噻烷慢性毒性、致癌与致畸研究[J].卫生毒理学杂志,1994,8(1):39-41.
• [4]蒋宪瑶,吴应竞,张爱华,等.大鼠多噻烷急性中毒的解毒研究[J].中华预防医学杂志,2000,34(3):146.
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• [6]GB 15670-1995农药登记毒理学试验方法.
• [7]何凤生.中华职业病学[M].北京:人民卫生出版社,1999.747-748.

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