贵州医科大学学报

1991, (03) 253-255

[打印本页] [关闭]
本期目录 | 过刊浏览 | 高级检索

小鼠HepA、S180腹水癌抑癌因子的分离提纯及其抑癌活性的观察
Purification of A Cancer-Suppressive Factor from the Ascites of Hepatoma and Sarcoma 180-Bearing Mice, and Its Cancer-Suppressive Activity

郑娅萍;王乐永;郭筱芬;何立望;
Zheng Yaping, et al Department of Biochemistry

摘要(Abstract):

从HepA小鼠和S180小鼠腹水液中分离提取抑癌因子,对其抑癌活性进行了观察。证明:经乙醇迥流、无水乙醇抽提、Sphadex G25分离后215nm第一峰即有明显的杀伤癌细胞的作用,且有交叉效应,即一种癌腹水制品对两种癌细胞均有杀伤作用。
A cancer-suppressive factor (CSF) was purified from the aseites of hepatoma and sarcoma 180-bearing mice. lts cancer-suppressive activity was investigated. The results showed that above-mentioned CSF acted as the killing of cancer eells both the hemogeneous and heterogeneous in the same potency, and its cancer-suppressive activity was increased following increase in concentration of the Sephadex-25 products. While the concentration of the SephadexG25 product from the aseites of hepatoma reached to 200μg per milliliter, the mortality of cancer cells was at 91 to 94 per cent for both the hemogeneous and hetero-geneous within 24 hours, and that of the product from the aseites of sarcoma 180-bearing mice reached to 200μg per milliliter, the percentage was in 81 to 84, comparatively.

关键词(KeyWords): 腹水;抑癌因子
ascites; cancer-suppressive factor

Abstract:

Keywords:

基金项目(Foundation):

作者(Author): 郑娅萍;王乐永;郭筱芬;何立望;
Zheng Yaping, et al Department of Biochemistry

Email:

文章评论(Comment):

序号(No.) 时间(Time) 反馈人(User) 邮箱(Email) 标题(Title) 内容(Content)
反馈人(User) 邮箱地址(Email)
反馈标题(Title)
反馈内容(Content)
扩展功能
本文信息
服务与反馈
本文关键词相关文章
本文作者相关文章
中国知网
分享