贵州医科大学学报

1988, (01) 29-32

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654-2滴眼剂的调节麻痹作用及其临床应用
CYCLOPLEGIC EFFECT OF ANISODAMINE EYE DROPS AND ITS CLINIC USE

白朝林;屠云松;张海燕;
Bai Chaolin,Dep of Ophthalmol

摘要(Abstract):

比较相同浓度和剂量的山茛菪硷与后马托品滴眼的调节麻痹作用。结果表明:山茛菪硷对睫状肌的麻痹作用大于后马托品;山茛菪硷对睫状肌与瞳孔括约肌的作用有选择性。文中还就山茛菪硷滴眼剂在眼科临床上的应用进行了探讨。
Anisodamine is an alkaloid derived from a plant"Anisodus Tangutus Pascher". 654-2 is its synthetic preparation. A comparative study of anisodamine with homatropine was done to assess the cycloplegic effect. 1% solutions of both as eye drops were given simultaneously to the right or left eye of the patient, respectively. When pupils dilated fully and light reflex disappeared, the residual accomodation ability was estimasec by an ophdthalmoscopyo. The results showed that the residual accomodation ability of 654-2 is significantly less than that of homatropine, when the same concentration and same volume of these two drugs are used.The residual cycloplegic effect of 654-2 is sshorter(only 1-2days) than that of homatropine anc there is no noticeable ystemic reaction. Because of these advantages, as a cycloplegic drug, 654-2 is preferable to homatropine.

关键词(KeyWords): 山莨菪硷;后马托品;眼调节
Aniscdamine Homatropine Accommodation, Ocular

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作者(Author): 白朝林;屠云松;张海燕;
Bai Chaolin,Dep of Ophthalmol

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DOI: 10.19367/j.cnki.1000-2707.1988.01.009

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