贵州医科大学学报

2009, v.34;No.140(05) 558-560

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呼吸科门诊患者抗感染药物应用分析
An Analysis on the Application of Anti-infection Medicines in Out-patients with Respiratory Diseases

卢蕾;魏建萍;黄艳云;熊怡;敖曼;
LU Lei,WEI Jianping,HUANG Yanyun,XIONG Yi,AO Man(The First People's Hospital of Guiyang City,Guiyang 550002,Guizhou,China)

摘要(Abstract):

目的:了解门诊呼吸科患者应用抗感染药物情况,为抗菌药的使用及管理提供依据。方法:随机抽取2008年每月各30份呼吸科门诊处方共360张,对痰培养、药敏试验、使用抗感染药物品种、使用率及相关费用进行分析。结果:痰培养阳性率为59.44%,抗感染药物使用率为83.61%,抗感染药物联用率为35.22%,抗感染药物总费用为48719.52元,用药频度(DDDs)排序前10位的药物均为广谱抗菌药,一些药物利用指数(DUI)相对较高,致病菌耐药率最高达73.7%(头孢唑啉)。结论:呼吸科门诊抗生素使用存在不合理情况,细菌耐药情况较严重。
Objective:To understand the application situation of anti-infection drugs in out-patients with respiratory diseases (OPR) and to provide scientific basis for proper application and administration of this kind of medicines. Methods: Thirty prescriptions for OPR per month in 2008 were randomly chosen. The sputum culture results,drug sensitivity test results,and variety,frequency ,and costs of medicines used of the related OPR were analyzed. Results: The positive rate of sputum culture was 59.44%,anti-infection drug application rate 83.61,combined drug application rate 35.22%,and the total cost 48,719.52 yuan. The top 10 drugs with highest application frequency were broad-spectrum antimicrobial agents,and some of them had relatively high drug use index (DUI). Conclusion: Inadequate use of antibiotics occurred in respiratory disease clinic,and the drug-resistance of bacteria is serious.

关键词(KeyWords): 抗感染药;门诊病人;呼吸系统;因素分析,统计学
anti-infective agents;outpatients;respiratory system;factor analysis,statistical

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作者(Author): 卢蕾;魏建萍;黄艳云;熊怡;敖曼;
LU Lei,WEI Jianping,HUANG Yanyun,XIONG Yi,AO Man(The First People's Hospital of Guiyang City,Guiyang 550002,Guizhou,China)

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DOI: 10.19367/j.cnki.1000-2707.2009.05.025

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