胃癌手术前后血浆PAI-1、t-PA水平及临床价值
杨芳;祭芬;黄吉娥;曾小菁;
摘要(Abstract):
目的:探讨胃癌患者手术前后血浆PAI-1、t-PA含量变化及临床价值。方法:采用双抗体夹心酶标免疫分析法,测定胃癌患者手术前后血浆PAI-1、t-PA与肿瘤转移和预后的关系。结果:胃癌术前PAI-1、t-PA均与非肿瘤对照组差异有统计学意义(P<0.05),行胃癌根治术后t-PA水平较术前差异有统计学意义(P<0.05);胃癌患者转移和无转移者PAI-1水平有统计学差异,而t-PA变化不大(P>0.05)。结论:血浆PAI-1、t-PA水平与胃癌的浸润及转移过程密切相关。
关键词(KeyWords):
胃癌;组织型纤溶酶原激活物;纤溶酶原激活物抑制剂;双抗体夹心酶标免疫分析法
基金项目(Foundation):
作者(Author):
杨芳;祭芬;黄吉娥;曾小菁;
Email:
DOI: 10.19367/j.cnki.1000-2707.2011.06.026
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