贵州医科大学学报

1985, (01) 58-61

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小儿急性白血病10例疗效观察
The Therapeutic Effect of 10 Cases of Acute Leukemia in Children

王雪芬;刘瑞琼;朱德芬;王宪侠;张惠;
Wang Xuefen, Department of Pediatrics

摘要(Abstract):

<正> 急性白血病是儿童中发病最高的恶性肿瘤,在有效治疗药物应用之前,其自然病程不到4个月。近年来由于治疗进展,缓解率大大提高。今将我科1978~1981年6月,住院经化疗的急性白血病患儿10例小结报道如下: 资料与方法一、治疗对象:全组均为不同病程(1周~4个月)初发病例,其中有1例在院外经过治疗后转来;年龄最小4岁,最大10岁;男女之比为3:2。二、白血病类型:表现淋巴细胞型(简称急淋)3例,其中第一型(L_1)2例,第二型(L_2)1例;急性非淋巴细胞型
The primary therapy of 10 cases of acute leukemia children from 1978 to 1981 was reported, in which 7 eases of acute myelocytic leukemia(AML)had 3 eases completely remited after treatment. 3 cases of acute lymphocytic leukemia (ALL) had remission. The total remission rat was 60%, which was much higher in ALL than AML. VMP, COAP and HOAP schedule had been used for inductiortherapy to ALL, AML type M_2 and type M_3. This represented that VMP schedule was effective both in ALL type L_1 and type L_2. The average duration of remission was 32 days. While the HOAP schedule could raise the remission rate of ALL tyPe M_3. The survival time of Patients in our group was short, on average about 81/2-19months. This might probably be due to improper maintenance of the theraputic schedule, and due to lack of synthetic operation for prophylaxis to the organ infiltration.

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作者(Author): 王雪芬;刘瑞琼;朱德芬;王宪侠;张惠;
Wang Xuefen, Department of Pediatrics

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DOI: 10.19367/j.cnki.1000-2707.1985.01.018

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