贵州医科大学学报

1996, (04)

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一贯煎及其多糖对小鼠红细胞和组织中SOD活性的作用
Effects of Yiguan Jian and its Polysaccharicles on the Activity of SOD in Red Cells and Tissues of Rats

王和生,陈永祥,靳凤云,吴家红
Wang Hesheng; et al(Department of Biochemistry Guiyang College of Traditional Chinese Medicine)

摘要(Abstract):

采用邻苯三酚自氧化法观察了一贯煎及其多糖对小鼠红细胞和组织中超氧化物歧化酶(SOD)活性的影响。结果表明:一贯煎及其多糖均能明显提高小鼠红细胞和组织中SOD的活性,与对照组相比有极显著性差异(P<0.001),说明其具有一定的抗衰老作用。
Yiguan Jian is a famous recipe in Ching dynasty. The effects of Yiguan Jian and its polysaccharicles on the activity SOD in rats' tissues and red cells were studied. SOD exists widety in the tissues of animals and plants. It can clear away free radical. After gave Yiguan Jian of 15 g/kg and the polysaccharides of 150 mg/kg.a day for 10 days by into gavage. The activity of SOD in red cells, liver and brain were determined by the method of pyrogallic acid autoxidation. The results were : (718±731 )u/ml in red cells, (6 384±989) u/g in liver and (4 567± 417) u/g in brain of control group,(935± 94) u/ml in red cells, (8 570± 899) u/g in liver and (7 381 ± 926) u/g in brain of polysaccharides group and (954± 86) u/ml in red cells, (9 041± 980) u/g in liver and (8 169± 934) u/g in brain of Yiguan Jian group. The results showed that the activity of SOD in rats' tissues and red cells given Yiguan Jian and its polysaccharides were higher significantly than that of control group (P< 0. 001 ) and that Yiguan Jian and its polysaccharides have certain antisenile effect.

关键词(KeyWords): 一贯煎,多糖类,超氧化物歧化酶类
Yiguan Jian; polysaccharides; superoxide dismutase

Abstract:

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作者(Author): 王和生,陈永祥,靳凤云,吴家红
Wang Hesheng; et al(Department of Biochemistry Guiyang College of Traditional Chinese Medicine)

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DOI: 10.19367/j.cnki.1000-2707.1996.04.011

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