贵州医科大学学报

2015, v.40;No.183(12) 1387-1390

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高压氧对脑膜瘤术后患者的治疗效果
Efficacy of Hyperbaric Oxygen Treatment on Meningioma Postoperative Patients

郁军超;于秋红;刘亚玲;薛连璧;
YU Junchao;YU Qiuhong;LIU Yaling;XUE Lianbi;Beijing Tiantan Hospital,Capital Medical University;

摘要(Abstract):

目的:探讨高压氧对脑膜瘤术后患者的治疗效果。方法:100例脑膜瘤手术切除患者,术后分为常规治疗组和高压氧治疗组,两组患者均给予常规治疗,高压氧组在常规治疗的基础上再给予高压氧治疗,比较两组患者治疗前后神经功能评分(NIHSS)评价神经功能障碍程度及颅脑影像学检查脑水肿体积变化。结果:脑膜瘤切除术后,常规治疗组和高压氧治疗组患者间NIHSS评分无显著差异(t=0.631,P=0.530),治疗后,两组患者NIHSS评分均明显降低,但高压氧组患者NIHSS减少量高于常规组,差异有统计学意义(t=2.147,P=0.034);治疗前,两组患者脑水肿体积间差异无统计学意义(t=0.368,P=0.714),治疗后,两组患者脑水肿体积均明显减小,但高压氧组患者脑水肿体积减少量高于常规组,差异有统计学意义(t=2.276,P=0.025)。结论:高压氧治疗能够有效减轻脑膜瘤术后患者的脑水肿,改善神经功能障碍,促进神经功能恢复。
Objective: To investigate the efficacy of hyperbaric oxygen( HBO) treatment on meningioma patients after surgery. Methods: One hundred meningioma patients after surgery were divided into two groups,the control group and HBO group. Patients in both groups were given routine treatment,and patients in HBO group additionally underwent HBO treatment. NIHSS score data and volumetric changes of the brain edema from both groups were collected before and after treatment for comparison.Results: There was no difference in NIHSS score between the two groups after surgery( t = 0. 631,P =0. 530),NIHSS score notably reduced in both groups after treatment. NIHSS score reduced more in HBO group than the control group( t = 2. 147,P = 0. 034). There was no difference in volume of brain edema before surgery between the two groups( t = 0. 368,P = 0. 714),brain edema notably reduced in both groups after treatment. The volume of brain edema in HBO group reduced more than the control group( t = 2. 276,P = 0. 025). Conclusion: HBO treatment can reduce brain edema and neurological dysfunction caused by meningioma after surgery.

关键词(KeyWords): 脑膜瘤;功能恢复;脑水肿;高压氧
meningioma;function recovery;brain edema;hyperbaric oxygen

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基金项目(Foundation): 国家自然科学基金(No.30972829)

作者(Author): 郁军超;于秋红;刘亚玲;薛连璧;
YU Junchao;YU Qiuhong;LIU Yaling;XUE Lianbi;Beijing Tiantan Hospital,Capital Medical University;

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DOI: 10.19367/j.cnki.1000-2707.2015.12.027

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