蔡立君;焦玲;楚兰;廖欣;

• 1:贵阳医学院
• 2:贵阳医学院附院神经内科
• 3:贵阳医学院附院影像科

摘要(Abstract)：

目的:分析肝豆状核变性患者的临床及头颅MRI特点。方法:分析25例肝豆状核变性患者的首发症状、合并损害、K-F环检查、血清铜蓝蛋白及头颅MRI异常资料。结果:25例患者中以神经精神症状首发者23例(92%),肝脏症状者2例(8%);合并肝硬化者6例(24%),合并血液系统损害者5例(20%);K-F环检查阳性20例(80%),血清铜蓝蛋白降低24例(96%);头颅MRI异常24例,累及双侧基底节区多个核团,对称分布。结论:以神经精神症状首诊的肝巨状核变性患者的头颅MRI扫描多有典型改变,结合铜蓝蛋白、K-F环等指标,可早期作出诊断。

关键词(KeyWords)： 肝豆状核变性;磁共振成像;血浆铜蓝蛋白;K-F环

Abstract:

Keywords:

基金项目(Foundation):

作者(Author): 蔡立君;焦玲;楚兰;廖欣;

Email:

DOI: 10.19367/j.cnki.1000-2707.2014.06.033

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