贵州医科大学学报

1989, (04) 241-246+325

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贵州省地方性克汀病脑CT和电生理改变
Changegs of Comptuted Tomography and Eleetrophyslology of the Brarn in the Endemic cretinism of Guizhou

时钟孚;卢亮;吴若秋;尚国燕;董佑忠;王小林;安怀略;赵明祥;卢卫;马启玲;候明泰;
Shi Zhongfu, et al Guiyang Medical College Affiliated Hospital

摘要(Abstract):

本文克汀病病人组颅脑CT表现特征:1.部分患者大脑皮质和髓质发育不良,表现为额叶、枕叶和顶叶的脑沟增宽(35%),脑外侧裂增宽(28%)。大脑皮质除额叶外各叶CT值均减低,侧脑室有前角扩大和体部相对性扩大。2.丘脑受到侵犯,表现为CT值减低和第三脑室扩大。3.脑干发育不良。4.部分(32%)患者小脑发育不良。本组患者BAEPs全部异常,其它检查的异常率SSEPs为27.2%,VEPs为25.5%,CET为81.8%,EEG为75.8%。
The CT scan apperance of brain retardation of development among cretins showed that widening of cerebral sulci, reduction the density of both the gray matter and white matter, decreasing of cerebral CT value and enlargement of the lateral brain ventricles. Decrease of CT value of thalamus and enlargement of third brain ventricle indicated the thalamus was also involved. The enlar- gement of cerebellopontine angle cistdrn, quardrigeminal cistern and cistern magna and fourth brain ventricle reprented the brain stem especially the pons was attacked. Cerebellar atrophy was detected 8 in 26 cretins (30.8%) . The brain evoked potentials in cretins were studied. The BAEPs in all 36 patients were found to be abnormal. The SSEPs were examined in 33 cases and showed abnormal changes in 9 cases (27.2%) . The abnormal rate in VEPs was 25.5% (8/34) . The abnormal rate of computer EEG tomography in cretins was 81.9%(27/ 34) . There were a localized high power band and low power band in the mi- dcentral or middle parieto-occipital region.

关键词(KeyWords): 克汀病;;脑;;X线计算机断层摄影术;;诱发电位;;脑电描记术
cretinism; brain; tomography, x-ray computed; evoked potentials; electroen cephalography

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作者(Author): 时钟孚;卢亮;吴若秋;尚国燕;董佑忠;王小林;安怀略;赵明祥;卢卫;马启玲;候明泰;
Shi Zhongfu, et al Guiyang Medical College Affiliated Hospital

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