贵州医科大学学报

2018, v.43;No.208(01) 79-83

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新生儿颅内出血的影响因素及预后
Analysis of Factors Related to Intracranial Hemorrhage and Prognosis of Neonates

者桂莲;霍志艳;张靖;刘苗;孙金侠;连喜院;
ZHE Guilian;HUO Zhiyan;ZHANG Jing;LIU Miao;SUN Jinxia;LIAN Xiyuan;Department of Neonates,Jingbian People's Hospital;Pingliang People's Hospital;

摘要(Abstract):

目的:探讨新生儿颅内出血的影响因素及预后。方法:选取443例新生儿,记录新生儿胎龄、出生体质量及是否有出生窒息,以及母亲年龄、产次、分娩方式、是否患有妊娠期高血压、糖尿病等情况;颅内出血患儿出生6个月后进行头颅CT复查,观察临床预后。结果:55例颅内出血患儿中,胎龄<37周的早产儿颅内出血发生率显著高于足月儿(χ2=55.545,P<0.001);年龄≥35岁、妊娠期高血压、糖尿病、剖宫产产妇的新生儿颅内出血发生率显著升高(P<0.05);多胎、早产、低出生体质量新生儿颅内出血治疗的总有效率显著低于单胎、足月、体质量正常新生儿(P<0.05);6个月后复查CT显示,43.8%蛛网膜下腔出血患儿接近正常。结论:早产、高龄、妊娠高血压、糖尿病、剖宫产产妇的新生儿更易发生颅内出血,其中新生儿为多胎、早产、低出生体重时颅内出血的疗效较差,蛛网膜下腔出血预后较好。
Objective: To investigate the factors related to intracranial hemorrhage and prognosis.Methods: 443 neonates were chosen as research targets. Collecting information on neonatal gestational age,birth weight,birth asphyxia or not,and their mother's age,number of delivery,delivery mode,whether suffering from pregnancy,hypertension,diabetes and other diseases; and CT detection was conducted after born for 6 months to observe the prognosis. Results: Incidence of intracranial hemorrhage in neonates with gestational age < 37 weeks was significantly higher than full time neonates( χ2=55. 545 P < 0. 001). Women with age≥35 years,gestational hypertension,diabetes mellitus and cesarean section showed higher incidence rate of having neonates with intracranial hemorrhage( P <0. 05); multiple birth,preterm birth and low birth weight infants with total effective ratio of intracranial hemorrhage were significantly lower than single birth,full-term birth and normal weight neonates( P< 0. 05); CT examination after 6 months showed 43. 8% neonates with subarachnoid hemorrhage got normal imaging. Conclusion: Neonates with premature birth and mother with older age,hypertension,diabetes and cesarean section were more susceptible to neonatal intracranial hemorrhage; multiple pregnancy,premature birth and low birth weight infants showed poor efficacy; subarachnoid hemorrhage with comparatively good prognosis.

关键词(KeyWords): 新生儿;颅内出血;影响因素;转归
neonate;intracranial hemorrhage;related factors;prognosis

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基金项目(Foundation): 甘肃省高等学校科学研究项目(2015B-138)

作者(Author): 者桂莲;霍志艳;张靖;刘苗;孙金侠;连喜院;
ZHE Guilian;HUO Zhiyan;ZHANG Jing;LIU Miao;SUN Jinxia;LIAN Xiyuan;Department of Neonates,Jingbian People's Hospital;Pingliang People's Hospital;

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