贵州医科大学学报

1997, (01)

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贵阳地区汉族及少数民族孕妇病毒与弓形虫抗体的检测
The Examination of Pregnant Noman Virus and Toxoplasma Gondii Antibody of Han Nationalily and the Minority Group in Guiyang

郭莉萍,左丽,万明明,陈景端,余士光,夏良树,洪秀华,余晓玲,禄永汉,董熙昌,陈艳,王宝林,毛克强
Guo Liping, et al Department of Gynecology and Obstetrics, Gulyang Medical College

摘要(Abstract):

测定了652例贵阳地区汉族及少数民族孕妇静脉血中巨细胞病毒(CMV)、风疹病毒(RV)、单纯疱疹病毒(HSV)、弓形虫(Tg)的特异性抗体,发现抗体阳性率高,RV及HSVIgG阳性有民族差异性(P<0.05),RVIgG及IgM阳性有年龄差异(P<0.05),CMVIgM阳性有年龄差异(P<0.01),CMVIgG阳性有孕期差异(P<0.01)。同时配对测定母血与脐血59例,发现3例病毒IgM阳性及1例TgCA阳性的孕妇其新生儿脐血中IgM及TgCA也阳性,提示病原体可直接通过胎盘感染胎儿。发现孕妇有上述4种病原体混合感染,混合感染无民族差异,认为RV、CMV、HSV、Tg作为孕妇的常规检测项目有重要意义,尤其是感染高发的年龄和孕期
In order to understand the infection of pregnant women’s RV, CMV, HSV and Tg, we have tested RV, CMV, HSV and Tg idiosyncrasy antibody IgG and IgM in their blood 564 examples of han nationality and 88 minority group Using ELISA method testing RV, CMV, HSV and Dot ELISA method testing Tg We discovered that the positive rate of RV, HSV and CMV IgG is high There is national difference between RV and HSV IgG positive and difference between RV IgG and IgM year by year The positive of RV IgG reaches the peak between the age of 20 to 30 The positive of CMV IgG has both age and term difference 33 mixing infection examples of 2 or 3 sorts of pathogen were discovered including 30 in Han nationality and 3 in minority group without national difference 59 examples of mother and navel blood have been pair tested 3 examples positive of virus IgG and IgM, one Tg IgG and GA has been discovered The newly born child with Tg positive is a anercephaly. It is regarding the virnus and Tg can infect foetus through placenta It is regarding that the routine testing of RV, HSV, CMV, and Tg is necessary

关键词(KeyWords): 妊娠,病毒,弓形体属
pregnancy; viruses; toxoplasma

Abstract:

Keywords:

基金项目(Foundation): 贵州省自然科学基金

作者(Author): 郭莉萍,左丽,万明明,陈景端,余士光,夏良树,洪秀华,余晓玲,禄永汉,董熙昌,陈艳,王宝林,毛克强
Guo Liping, et al Department of Gynecology and Obstetrics, Gulyang Medical College

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DOI: 10.19367/j.cnki.1000-2707.1997.01.009

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