贵州医科大学学报

2018, v.43;No.214(07) 816-818+823

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多发与单发乙肝相关肝细胞癌根治术后的复发率及总生存率
Analysis of Recurrence Rate and Overall Survival Rate of Multiple-Nodular and Single-Nodular Hepatitis B Virus-Related Hepatocellular Carcinoma after Radical Resection

朱海涛;刘哲豪;
ZHU Haitao;LIU Zhehao;Department of Hepatobiliary Surgery,Affiliated Hospital of Guizhou Medical University;

摘要(Abstract):

目的:探讨多发与单发乙肝相关肝细胞癌根治术后的复发率和总生存率。方法:回顾性分析28例乙肝相关肝细胞癌患者的随访资料,多发瘤患者15例(多发瘤组)和单发瘤患者13例(单发瘤组),所有患者均已行肝癌根治术,术后平均随访时间为18.1个月,术后每3个月随访1次,比较2组患者根治术后随访期内的复发率与总生存率。结果:单发瘤组患者术后复发率低于多发瘤组患者,总生存率高于多发瘤组患者,差异有统计学意义(P<0.05)。结论:单发乙肝相关性肝细胞癌患者根治术后预后优于多发肿瘤患者。
Objective: To investigate the overall survival( OS) and time to recurrence( TTR) between multiple-nodular and single-nodular Hepatitis B virus( HBV)-related hepatocellular carcinoma( HCC) after radical resection. Methods: Retrospective analysis on follow up record of 28 HBV-related HCC patients. All patients received radical resection as the treatment of HCC. 15 were multiplenodular HCC patients( multiple-nodular group),13 were single-nodular HCC patients( single-nodular group). Average follow up time is 18. 1 months after surgery,once in every three months. Overall survival rate and time to recurrence rate were analyzed between both groups. Results: The TTR of singlenodular group was lower than that of multiple-nodular group,while OS was higher than that of multiplenodular HCC group,differences were statistically significant( P < 0. 05). Conclusion: The prognosis after radical resection of single-nodular HCC patients was better than that of multiple-nodular HCC patients.

关键词(KeyWords): 癌,肝细胞;肝炎,乙型;随访研究;肝癌根治术;复发率;生存率
carcinoma,hepatocellular;hepatitis B-virus;Follow up study;radical resection of liver cancer;recurrence rate;survival rate

Abstract:

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基金项目(Foundation): 贵州省科技计划项目[黔科合LH字(2016)7232号]

作者(Author): 朱海涛;刘哲豪;
ZHU Haitao;LIU Zhehao;Department of Hepatobiliary Surgery,Affiliated Hospital of Guizhou Medical University;

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DOI: 10.19367/j.cnki.1000-2707.2018.07.016

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