贵州医科大学学报

2015, v.40;No.182(11) 1259-1261

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腹腔镜治疗结肠癌的远期疗效
Comparison of Long-Term efficacy of Laparoscope in the Treatment of Colon Cancer

吴松;杨成林;
WU Song;YANG Chenglin;Pingli County Hospital;Central Hospital of Ankang;

摘要(Abstract):

目的:探讨腹腔镜手术在结肠癌的治疗中的远期疗效。方法:179例结肠癌患者,按照手术方法分为观察组和对照组,观察组采用腹腔镜手术,对照组采用开放手术,比较两组结肠癌手术用时、术中出血量、通气时间、进食时间及清除的淋巴数,观察随访13~61个月的肿瘤局部复发、远处转移、远期并发症及患者3年和5年生存率;评估肿瘤分期与远期疗效的关系。结果:两组结肠癌患者除手术用时、淋巴清除数目外,术中出血量、通气时间及进食时间比较观察组优于对照组(P<0.05);两组结肠癌患者远期疗效比较,差异无统计学意义(P>0.05);结肠癌Ⅲ、Ⅳ期患者局部复发、远处转移、远期并发症均高于Ⅰ、Ⅱ期患者,3年和5年生存率显著低于Ⅰ、Ⅱ期患者,差异有统计学意义(P<0.05)。结论:腹腔镜手术治疗结肠癌远期疗效与开放手术相当,术后的预后与肿瘤分期有关。
Objective: To investigate the long-term efficacy of laparoscope operation in the treatment of colon cancer. Methods: A total of 179 patients with colorectal cancer was divided into LS group and OS group according to the operation method. LS group was treated with laparoscopic operation,OS group was treated with open operation,and treatment results were evaluated. Comparing surgery time,blood loss,duration of ventilation,feeding time and lymphocyte count; observing follow-up visit local tumor recurrence in 13 to 61 months,3 years and 5 years survival rate; evaluating the relationship between tumor staging and long term efficacy. Results: In LS group,the amount of intraoperative bleeding,duration of ventilation,the time of food intake were lower than OS group( P < 0. 05); long term efficacy comparison showed no statistical significance( P > 0. 05). The incidences of local recurrence,distant metastasis,and long-term complication patients with stage Ⅲ and Ⅳ was significantly higher than those of patients with stage Ⅰ and Ⅱ,and the survival rates of 3 years and 5 years were significantly lower than those in patients with stage Ⅰ and Ⅱ,and the difference was statistically significant( P < 0. 05). Conclusion: In the treatment of colon cancer,the laparoscope operation is safe and effective,tumor staging is closely related to the prognosis of patients.

关键词(KeyWords): 腹腔镜;结肠肿瘤;远期疗效;手术后并发症
laparoscope;colorectal cancer;long term curative effect;postoperative complications

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作者(Author): 吴松;杨成林;
WU Song;YANG Chenglin;Pingli County Hospital;Central Hospital of Ankang;

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DOI: 10.19367/j.cnki.1000-2707.2015.11.035

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