王勒渝;许定珍;许才坤;高华胜;熊玉霞;曹素元;李守兰;
Wang Leyu Department of Pathology, Guiyang College of Traditional Chinese Medicine

• 1: 贵阳中医学院病理学教研室
• 2:贵阳中医学院病理学教研室
• 3:贵阳中医学院病理学教研室
• 4:贵阳中医学院病理学教研室

摘要(Abstract)：

用大耳白兔30只,分三组进行实验。对照组以高胆固醇-高脂肪饮食复制成动脉粥样硬化症模型。服药组除喂以造型剂外加服“冠心通络舒郁丸”,共2_0周。实验结果,服药组与对照组比较,血液流变学得到明显的改善,经统计学处理差异非常显著。
Experimental atherosclerosis was produced by feeding the rabbits with high cholesterol-high fat diet. 30 rabbits were randomly divided into 3 groups of 10 animals. 3 groups were treated for 20 weeks, respectively with (A)nor- mal group-normal diet, (B) control group-high cholesterol-high fat diet and (C) experimental group- (B) diet plus "Guan xin tong luo shu yu pill". The blood rheology methods, containing 8 indexes: i. e. whole blood viscosity, plasms viscosity, whole blood reduction viscosity, RBC of electrophoresis, erythrocyte sedimentation rate, hematocrit, erythrocyte equational coefficient K and erythrocyte agglutiation index, were to be, taken at pre-and-post experi ment. At the end to experiment, the hemorrheologic difference between B and C group showed a high significance statistically, the homorrheology of the rab- bit Was significantly ameliorated by the "Guan xin tong luo sha yu pill". In the present study, it is suggested that a definite experimental criterion is provided for the clinical use of "Guan xin tong luo shu yu pill".

关键词(KeyWords)： 冠心通络舒郁丸;血液流变学动脉粥样硬化症
Guan xin tong luo shu yu pill; blood rheology; atherosclerosis

Abstract:

Keywords:

基金项目(Foundation):

作者(Author): 王勒渝;许定珍;许才坤;高华胜;熊玉霞;曹素元;李守兰;
Wang Leyu Department of Pathology, Guiyang College of Traditional Chinese Medicine

Email:

DOI: 10.19367/j.cnki.1000-2707.1989.02.008

参考文献(References)：

• 1． 许才坤,等。“冠心通络舒郁丸”对家兔动脉粥样硬化症作用的病理观察。贵州医药1988;12(3) :140～141。
• 2． 张尧庭,方开泰。多元统计分析引论。北京:科学出版社,1982:163～165。
• 3． 梁子钧。血液流变学及其在医学临床上的应用。生理科学进展1979;10:304。
• 4． 陈雅君,等。家兔实验性动脉粥样硬化模型的血液流变学观察。中华心血管病杂志1982;10:297。

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