贵州医科大学学报

1996, (03)

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慢性肾脏病患者血清内源性洋地黄物质的变化
The Changed of serum Digoxin-like Substances in Patients with Chronic Renal Disease

朱春玲,卢源,张瑞芬,彭红英,席学丽,彭建强
Zhu Chunling;et al(Department of lntenal Medicine,Guiyang Medical College)

摘要(Abstract):

测定了41例慢性肾脏疾病患者血清内源性洋地黄物质(EDIS)的含量。结果发现:慢性肾功能衰竭、慢性肾小球肾炎、肾后综合征及慢性肾盂肾炎患者血清EDLS均值均显著高于正常(P<0.05)。在慢性肾功能衰竭,血清EDLS的含量与血肌酐呈正相关,提示血清EDLS水平可作为估计肾功能损害程度及预后的一个指标。
The levels of digoxin-like substance were measured by radioimmunoassory in 41 cases of patients with chronic renal disease and 30 controls.The mean level of serum digoxin-like substance in the patients(0.124 2±0.152 6μg/)was higher than of the control(0.04±0.07μg/L),P<0. 05. In the patients groups with chronic renal failure(22 cases), the level of serum digoxin-like substance was remarkably higher,and had a positive correlation with serum creatinine(r=0.55 1 08,P<0. 05).The date indicated that the level of serum digoxin-like substance might can be indicator for evaluating the prognosis and siniation of the patients with chronic renal deficiency.

关键词(KeyWords): 肾脏疾病,内源性洋地黄物质
chronic renal disease;digoxin-like substance

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作者(Author): 朱春玲,卢源,张瑞芬,彭红英,席学丽,彭建强
Zhu Chunling;et al(Department of lntenal Medicine,Guiyang Medical College)

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