贵州医科大学学报

1998, (04)

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酶联检测CA_(125)在妇科的应用
Use of CA 125 Level Detecting by ELISA in Gynecologic Clinic

周遵伦,雷后康,李荣荣,杨英捷,李佳筑
Zhou Zhunlun,et al. Department of Gynecology, Affiliated Hospital of Guiyang Medical College

摘要(Abstract):

采用酶联法(ELISA)检测了229例妇科患者的血清上皮性卵巢癌抗原(CA125),并进行分析。结果:1卵巢癌患者血清CA125明显高于良性病例,两者阳性率分别为8125%和89%,有极显著性差异(P<0001),其中浆液性癌阳性率明显高于粘液性癌,分别为937%和70%;2内膜异位症CA125水平亦升高,阳性率为526%。结论:ELISA检测血清CA125与传统的放免法(RIA)相比,具有同等的诊断价值,在应用上具有便捷,药盒保存时间长,无污染等优点。
To investigate clinical signifcance of detecting the serum CA 125 in Engyme-Linked immuno sorbent assay (ELISA). Examine serum CA 125 contens of 229 gynaecopathia patients in ELISA and clinical analysis of them.1 The serum CA 125 of ovarion caners were obviously higher than those benign diseases (P<0 001). The positive ratio of ovarion cancers is 81 25% and that of the benige clisenses is 8.9%. In Which the positive ratio of seveus cancers in obviously higher than that of mucinous cancers (97.3%,70%).2 The CA 125 level of endometriosis increases to positive ratio is 52.6%. CA 125 is a senstitive sign of epithelial cancer. Compared with traclional RIA, ELISA examing serum CA 125 has the same chiagnostic value, additional, it has some advantages: giuck and convenient opertion, long-time coseration in a medicine-box,no polution, reguire of test condition is not high rank, so that it is suitable to be applied in basic unit hospital and general surrey, it is a method worth popularizing.

关键词(KeyWords): 酶联免疫吸附测定,抗原.肿瘤相关.碳水化合物,孵巢,癌
enzyme linked immunosobent assay; antigens, tumor asseciatel, carbohyarate; qvary; carcinoma

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作者(Author): 周遵伦,雷后康,李荣荣,杨英捷,李佳筑
Zhou Zhunlun,et al. Department of Gynecology, Affiliated Hospital of Guiyang Medical College

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