吗啡对清醒可活动的动物不同脑区单细胞放电的影响
■代麟;殷松生;陆莲华;曾凡瑛;刘迪成;周会举;
摘要(Abstract):
<正> 吗啡与内源性类吗啡物质的中枢作用机制尚末完全阐明。近年来有人(Longo1962,Bradley 1968,Navarro 1971)观察对脑电(E E G)皮层诱发电位(Ruben,1979 Heranndez.1981)以及脑不同部位细胞放电的影响。过去我们的工作也曾观察过吗啡对刺激猫牙髓所引起的皮层诱发电位的抑制作用。但用粗电极或一般脑电的记录方法,很难找出有特殊意义的变化。用微电泳的方法观察吗啡与内源性类吗啡物质对脑细胞放电的影响近来报导颇多(见North 1979的综述)。用微电泳,所给药物直接作用于所记录的细胞,实验结果便于分析,但作用较为局限,也不可能同时观察动物的行
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作者(Author):
■代麟;殷松生;陆莲华;曾凡瑛;刘迪成;周会举;
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DOI: 10.19367/j.cnki.1000-2707.1982.01.008
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