贵州医科大学学报

2015, v.40;No.173(02) 153-155

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子宫内膜轻微吸刮术改善反复流产妇女子宫内膜容受性的临床研究
The Clinical Research of Endometrial Scratching on Improving Endometrium Receptivity for Repeated Abortion Women

陈琨;李琴芬;
CHEN Kun;LI Qinfen;Department of Obstetrics and Gynecology,the Affiliated Hospital of Guiyang Medical College;

摘要(Abstract):

目的:探讨子宫内膜轻微吸刮术对反复流产妇女子宫内膜容受性的影响。方法:100例反复流产患者随机分为实验组和对照组,实验组在月经第2天行子宫内膜轻微吸刮术,对照组不予任何处理,两组受检者在B超显示卵泡≥18 cm时指导同房,观察两组患者的临床妊娠率、流产率和活产率。结果:两组患者年龄、流产次数差异均无统计学意义(P>0.05),实验组临床妊娠率36%、流产率6%、活产率30%,对照组临床妊娠率30%、流产率24%、活产率6%,实验组和对照组临床妊娠率差异没有统计学意义(P>0.05),但实验组有升高趋势;实验组流产率比对照组降低(P<0.05),活产率升高(P<0.01),实验组病人在进行子宫内膜搔刮术后均未出现不良反应。结论:子宫内膜轻微吸刮术显著提高子宫内膜容受性,降低流产率,提高临床活产率,安全性好。
Objective: To investigate the effect of endometrial slight scratching on endometrium receptivity for repeated abortion women. Methods: One hundred women with recurrent abortion medical history were randomly divided into experimental group( 50 cases) and control group( 50 cases); on the 2ndday of menstrual,practicing endometrial slight scratching absorption technique for the experimental group,and none for the control group. All the patients were instructed to have intercourse when ultrasound test shows the ovarian follicle ≥18 cm. Both groups of patients were observed concerning clinical pregnancy rate,spontaneous abortion rate and live birth rates. Results: Differences of age and number of abortions of both groups had no statistical significance( P > 0. 05),clinical pregnancy rate of the experimental group was 36%,spontaneous abortion rate was 6%,and live birth rate was 30%;clinical pregnancy rate of control group was 30%,spontaneous abortion rate was 24%,live birth rate was 6%,differences between experimental group and control group in clinical pregnancy rate had no statistical significance( P > 0. 05),but exhibited rising trend; the experimental group showed a significant reduction in spontaneous abortion rate compared with the control group( P < 0. 05),live-birth rate increased significantly( P < 0. 01). Experiment group patients with endometrial scratching operation showed no adverse reactions. Conclusions: Endometrial slight scratching technique is safe to improve the receptivity of endometrium,reduces the spontaneous abortion rate,improve clinical live-birth rate.

关键词(KeyWords): 妇科外科手术;子宫内膜轻微吸刮术;流产;子宫内膜容受性;疗效
gynecologic surgical procedures;endometrial slight scratching;abortion;endometrium receptivity;curative effect

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作者(Author): 陈琨;李琴芬;
CHEN Kun;LI Qinfen;Department of Obstetrics and Gynecology,the Affiliated Hospital of Guiyang Medical College;

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