贵州医科大学学报

2013, (01) 44-49

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磁共振动脉自旋标记灌注成像在胶质瘤及脑转移瘤诊断中的应用
The Application of Arterial Spin Labeling Perfusion Magnetic Resonance Imaging in Diagnosis of Gliomas and Its Brain Metastases

冯辉;沈桂权;
FENG Hui,SHEN Guiquan(Department of Radiology,the Affiliated Hospital of Guiyang Medical College,Guiyang 550004,Guizhou,China)

摘要(Abstract):

目的:探讨磁共振动脉自旋标记(ASL)灌注成像技术在胶质瘤术前分级及胶质瘤与脑转移瘤术前鉴别诊断中的临床应用价值。方法:收集颅内肿瘤患者50例,使用1.5 T MR成像系统对所有患者行常规MR及ASL扫描。结果:低级别胶质瘤的肿瘤相对血流量(rTBF)低于高级别胶质瘤,两者间的差异具有统计学意义(P﹤0.05);脑转移瘤的rTBF明显高于低级别胶质瘤,两者间的差异具有统计学意义(P﹤0.01);脑转移瘤的rTBF与高级别胶质瘤的rTBF相近,两者的差异无统计学意义(P>0.05)。结论:ASL灌注成像技术有助于胶质瘤术前分级诊断及胶质瘤与脑转移瘤术前鉴别诊断。
Objective: To investigate the diagnostic value of arterial spin labeling(ASL) perfusion magnetic resonance imaging in preoperative grading of gliomas and differential diagnosis of its brain metastases.Methods: Conventional MR imaging and ASL perfusion magnetic resonance imaging were carried out to 50 patients with intracranial tumors by using 1.5 T MR imaging system,and the images were analyzed.Results: The relative blood flow(rTBF) values of low-grade gliomas was lower than that of high-grade gliomas,the difference was significant(P<0.05);The rTBF values of brain metastases cases were significantly higher than those of low-grade gliomas(P<0.01);In brain metastases cases,rTBF values were similar with those of high-grade gliomas,and the difference was not significant(P>0.05).Conclusion: ASL perfusion magnetic resonance imaging is helpful to distinguishing low-grade gliomas from high-grade gliomas and distinguishing simple gliomas from those brain metastases cases before operation.

关键词(KeyWords): 神经胶质瘤;肿瘤转移;磁共振成像;动脉自旋标记;诊断
glioma;neoplasm metastasis;magnetic resonance imaging;arterial spin labeling;diagnosis

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作者(Author): 冯辉;沈桂权;
FENG Hui,SHEN Guiquan(Department of Radiology,the Affiliated Hospital of Guiyang Medical College,Guiyang 550004,Guizhou,China)

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