贵州医科大学学报

1995, (02)

[打印本页] [关闭]
本期目录(Current Issue) | 过刊浏览(Past Issue) | 高级检索(Advanced Search)

免疫放射法测定甲状腺和非甲状腺疾病患者血清TSH水平
Clinical Value of Measurement of Serum TSH in the Patients with Thyroid Diseases and Nonthyroidal Illness by Immunoradiometric Assay

吴艺捷,时钟孚,张家秀
Wu Yijie,et al.(Department of Endocrinology,Affiliated Hospital of Guiyang Medical College)

摘要(Abstract):

用免疫放射法(IRMA)测定了378例各种甲状腺疾病及非甲状腺疾病(NTI)患者血清TSH以及T_3、T_4和FT_4水平。结果:未治疗或症状未控制的甲亢患者血清TSH明显低于对照组,甲亢治愈者则恢复正常。甲减者TSH变化与其临床表现相一致。在碘缺乏病区TSH-IRMA能较T_3、T_4更好的反映居民的碘营养状况。在NTI时虽有T_3、T_4的改变,但TSH-IRMA和FT_4结果大多为正常。本文表明TSH-IRMA在评估甲状腺功能状态时有较好的敏感性及特异性。
Serum TSH levels were measured by a sensitive immunoradiometric assay(IRMA) and serum T3, T4 and FT4 levels were also measured by radioimmunoassay (RIA)in 378 patients with various thyroid diseases or nonthyroidal illness(NTI). The results showed that serum TSH levels were significantly lower in untreated and non-controlled hyperthyroid patients as compared with controls.The subnormal TSH values were found to become normal in clinical euthyroid patients.The changes of serum TSH leveis in the patients with hypothyroidism were consistency with their clinical symptoms.The TSH-IRMA was a better indicator as the iodine nutrition condition of the inhabitants in the iodine deficiency disorders areas than T3 and T4 assay. Although some of patients with NTI had abnormal T3 and T4 levels, most of them still had normal TSH-IRMA and FT4 levels.This study suggested that TSH-IRMA presented a good sensitivity and specificity in assessment of thyroid function starus.

关键词(KeyWords): 促甲状腺素,免疫测定,甲状腺疾病
thyrotropin;immunoassay;thyroid diseases

Abstract:

Keywords:

基金项目(Foundation):

作者(Author): 吴艺捷,时钟孚,张家秀
Wu Yijie,et al.(Department of Endocrinology,Affiliated Hospital of Guiyang Medical College)

Email:

文章评论(Comment):

序号(No.) 时间(Time) 反馈人(User) 邮箱(Email) 标题(Title) 内容(Content)
反馈人(User) 邮箱地址(Email)
反馈标题(Title)
反馈内容(Content)
扩展功能
本文信息
服务与反馈
本文关键词相关文章
本文作者相关文章
中国知网
分享