贵州医科大学学报

1993, (02) 103-105

[打印本页] [关闭]
本期目录(Current Issue) | 过刊浏览(Past Issue) | 高级检索(Advanced Search)

贵州苗族人群HLAⅡ类基因的多态性
The Polymorphism of HLA Class Ⅱ Gene in Guizhou Miao Population

刘若英;郑周瑛;吴亚云;李梅松;
Liu Ruoying, et al. Department of Clinical Microbiology & Immunology

摘要(Abstract):

用HLAⅡ类抗原抗血清120份,检测了58例贵州苗族人群的HLA-DR和-DQ抗原。贵州苗族最常见的Ⅱ类抗原是HLA DR9、DRW12、DQW1和DQW7,它们的基因频率分别是0.172,0.189,0.377和0.293。贵州苗族人群HLA5位点单倍型频率大于0.02的有7条,频率最高的是:HLA A11、CW9、B13、DRW15、OQW1,频率达0.043。本研究支持在HLA多态性上,中华民族可划分为南北两大群的观点。
With standard methods and 120 of 11th International Histocompatibility Workshop and Comference second set antisera, the HLA-DR,-DQ antigens of 58 non-kindred Guizhou Miao adults were typed. The most frequent alleles found in Guizhou Miao population were : HLA DR9 gene frequency 0.172,DRW12 gene frequency 0.189, DQW1 gene frequency 0.377, DQW7 gene frequency 0.293. There were 7 of five-locus haplotype which frequency was higher than 0.02 in Guizhou Miao population.The highest was HLA All, CW9.B13, DRW15, DQW1. Our present data offered further evidence confirming that Guizhou Han, Miao, Buyi and southern Han constituted the southern Chinese population and supported that the Chinese Nation comprised two major groups.

关键词(KeyWords): 人类学;人白细胞抗原;贵州苗族
anthropology;HLA antigens;Guizhou Miao nation

Abstract:

Keywords:

基金项目(Foundation):

作者(Author): 刘若英;郑周瑛;吴亚云;李梅松;
Liu Ruoying, et al. Department of Clinical Microbiology & Immunology

Email:

DOI: 10.19367/j.cnki.1000-2707.1993.02.006

文章评论(Comment):

序号(No.) 时间(Time) 反馈人(User) 邮箱(Email) 标题(Title) 内容(Content)
反馈人(User) 邮箱地址(Email)
反馈标题(Title)
反馈内容(Content)
扩展功能
本文信息
服务与反馈
本文关键词相关文章
本文作者相关文章
中国知网
分享