贵州医科大学学报

1988, (02) 232-235

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羟丙基甲基纤维素薄膜包衣的实验研究
EXPERIMENTAL RESEARCH ON FILM COATED TABLET OF HPMC

孙健;李达富;
Sun Jian,Zhejiang Research Institute of TCM

摘要(Abstract):

用羟丙基甲基纤维素(HPMC)作包衣材料包出的薄膜包衣片,同糖衣片比较,其掩盖药味、外观等性能同糖衣片基本接近,而吸湿度、崩解度、硬度、脆碎度、包衣后增重等质量指标均优于糖衣片。本文介绍了薄膜包衣的实验研究,并就包衣结果及过程中出现的问题进行了讨沦。
The HPMC was used as the coating material in film coated tablet,the fu- nction of which is nearly equal to that of sugar coated tablet in outward app- earance and cancealing drug taste,and the film coated tablet is superior to the sugar coated tablet in the quality index of hygroscopicity,collapsing cha- reacter,hardness,brittleness and increased weight.The xperimental research of film coated tablet was presented in this article,and the problems durning experiment and the problems of result are also discussed.

关键词(KeyWords): 羟丙基甲基纤维素;片剂;制药工业
HPMC(hydroxypropy lmethylcellulose);Tablets Drug industry

Abstract:

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作者(Author): 孙健;李达富;
Sun Jian,Zhejiang Research Institute of TCM

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DOI: 10.19367/j.cnki.1000-2707.1988.02.026

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