贵州医科大学学报

1991, (04) 335-338+396

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苦瓜浸膏局部应用对小鼠生育力的影响
Influence on the Fertility by Applying Locally Momordica Charantia Extract on the Scrotum of Mice

高晓勤;覃国芳;李远慧;
Gao Xiaoqin, et al Department of Histology and Embryology

摘要(Abstract):

采用苦瓜浸膏对昆明系雄性成年小白鼠进行阴囊涂擦,结果发现:部分睾丸曲细精管上皮排列紊乱,层次减少。精于细胞内出现较大的空泡,线粒体肿胀,变态期精子顶体膜增厚、皱缩。精子数量减少,活力下降及畸变率增高。说明苦瓜浸膏局部应用,可阻抗精子的阶段发育,达到男性抗生育力目的。
Momordica charantia, containing anti-male-fertility compositions, was applied locally on the scrotum of adult Kun Ming line mice. The results showed that the seminiferous tubules and spermatogenous cells were damaged in different degrees. The spermatids exhibited degenerative changes and reduced in unmber as well. Under the electron microscope the spermatids showed swelling of the mitochondria, appeared large bubbles and abnormal acrosomes in the protoplasm. A marked decrease of spermmotility and incre ase of abnormal spermatozoons were observed. Local applying momordica charantia extract in mice might arrest spermiogenesis and existing an anti male-fertility effect.

关键词(KeyWords): 苦瓜浸膏;精子;生育力;小鼠
momordica charantia extract; spermatozoa. fertility; mice

Abstract:

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作者(Author): 高晓勤;覃国芳;李远慧;
Gao Xiaoqin, et al Department of Histology and Embryology

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DOI: 10.19367/j.cnki.1000-2707.1991.04.014

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