贵州医科大学学报

1994, (01)

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血脂和载脂蛋白A_1、B_(100)测定对NIDDM血管病变的诊断价值
The Measurement of the Serum Lipid,Apolipoprotein A_1 and B_(100) on the Diagnosis Values of Vascular Complications of NIDDM Patients

马莉,吴艺捷,罗学贵
Ma Li, et al.(Department of Clinical BiochemicalLaboratories,Guiyang Medical Collage)

摘要(Abstract):

测定352例有或无血管病变的非胰岛素依赖型糖尿病(NIDDM)病人及44例正常人的血清甘油三酯(TG)、总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-ch)、低密度脂蛋白胆固醇(LDL-ch),载脂蛋白A1(ApoA1)、载脂蛋白B(100)(ApoB(100))的水平。分析了这些指标与NIDDM并发血管病变的相关性。结果:NIDDM并发血管病变各组与NIDDM无并发症组及正常对照组之间比较LDL-ch和ApoB(100)水平升高;ApoA1/ApoB(100)比值降低。提示上述指标可作为NIDDM并发血管病变的预测指标。
Serum triglyceride(TG), total cholesterol(TC), high density lipoprotein─cholesterol(HDL-ch), low density lipoprotein-cholesterol(LDL-ch), apolipoprotein A1(Apo A1) and apolipoprotein B(100)(Apo B(100) were measured in 52 non-insulin-dependent diabetes mellitus (NIDDM) patients with or without vascular complications and 44 normal volunteers as control.The correlation of the indices and the vascular complications were also analyzed. The results showed that the mean values of LDL-ch and Apo A1/Apo B(100) in the NIDDM patients with vascular complications were significantly higher than those in the NIDDM patients without vascular complications as well as the control.But the ratio of Apo A1/Apo B(100) in the NIDDM patients with vascular complications was below that of the contrlo. Our data suggests that serum LDL-chand Apo B(100) as well as the ratio of Apo A1/APO B(100) might be a good indicator of NIDDM patients existed vascular complications.

关键词(KeyWords): 非胰岛素依赖型糖尿病,血管疾病,载脂蛋白A_1,载脂蛋白B_(100)
diabetes mellitus, non-insulin-dependent; vascular diseases; Apolipoprotein A_1;Apolipoprotein B_(100)

Abstract:

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作者(Author): 马莉,吴艺捷,罗学贵
Ma Li, et al.(Department of Clinical BiochemicalLaboratories,Guiyang Medical Collage)

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DOI: 10.19367/j.cnki.1000-2707.1994.01.012

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