段建东;卢亮;赵明祥;时钟孚;尚国燕;董佑忠;吴若秋;宋开瑢;卢卫;魏新建;张启文;
Duan Jiandong,Guizhou Geriatrics Department

• 1: 贵州省老年医学研究室
• 2:贵州省老年医学研究室
• 3:贵州省老年医学研究室
• 4:贵阳医学院内科学教研室

摘要(Abstract)：

用脑等电位图等手段对26例青少年克汀病患者进行检查,并与同龄的22例正常人作对比。结果发现青少年克汀病患者α频带的能量降低,分布呈广泛性改变;θ频带分布亦呈广泛性改变,能量无明显增高。本文将这些结果与头颅 CT、临床症征作了对比分析,考虑与克汀病脑部弥漫性病变和额叶萎缩有关。
Computer EEG Topography(CET)was carried out in 26 cases of creti- nism from 10-19 years old and 22 examinees of normal control at the similar age range to show the changes of brain bioelectrical activity.By comparing with the normal aontrol group,the CET changes of critinism were as follows: the alpha frequency band shifted to parietal and frontal regions;the theta frequency band appeared on temporal and parietal regions.By statistical of both groups,these data are very significant.Energy of alpha band was decre- ased in cretins.These findings may be due to brain atrophy of cretin,parti- culary the atrophy of frontal lobe.Correlative study with CT scanning in cretinism,the very significant change of CET in cretinism associated with very prominent brain atrophy in cretinism.

关键词(KeyWords)： 克汀病;脑等电位图;频带;能量值;X 线计算机断层摄影术
Cretinism;Computer EEG Topography;Frequency band;Energy Tomography;X-ray Computed

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基金项目(Foundation):

作者(Author): 段建东;卢亮;赵明祥;时钟孚;尚国燕;董佑忠;吴若秋;宋开瑢;卢卫;魏新建;张启文;
Duan Jiandong,Guizhou Geriatrics Department

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参考文献(References)：

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• 2． John R.Hughes,et al.EEG and evoked potentials in psychiatry and behavioral neurology.USA:Butterworth publishers,1983:231-273．
• 3． 冯应琨.临床脑电图学.北京:人民卫生出版社,1980:255．
• 4． Huttenlocher PR.Dendritic development in neocortex of children with mnetaldefect and infantile spasms.Neurology 1974:24:203-210．
• 5． Standury JB,et al.Endemic goiter and cretinism.New York:John Wiley and Sons,1980:445．

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