贵州医科大学学报

2015, v.40;No.179(08) 873-875

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氨氯地平阿托伐他汀钙片治疗高血压合并冠心病
A Study on the Effect of Amlodipine Atorvastatin Calcium Tablet on Patients with Hypertension with Coronary Heart Disease

陈鼎;张贤春;陈漠水;
CHEN Ding;ZHANG Xianchun;CHEN Moshui;General Department,Branch Hospital of Haikou People's Hospital;Department of Cardiology,Haikou People's Hospital;

摘要(Abstract):

目的:观察氨氯地平阿托伐他汀钙片在高血压合并冠心病治疗效果。方法:收集92例高血压合并冠心病患者,根据不同治疗方案将患者分为对照组和实验组,对照组采用硝苯地平缓释片治疗,实验组采用实氨氯地平阿托伐他汀钙片治疗,比较两组血压、总胆固醇、甘油三酯等指标,观察两组的治疗效果。结果:两组治疗前的收缩压与舒张压比较均无统计学意义(P>0.05);治疗后,实验组的收缩压与舒张压均显著低于对照组(P<0.05),治疗后的血压均明显下降,与治疗前比较差异有统计学意义(P<0.05);实验组总有效率为95.65%,对照组总有效率为82.61%(P<0.05);实验组TC、TG、LDL-L、HDL-L指标显著低于对照组(P<0.05)。结论:高血压合并冠心病应用氨氯地平阿托伐他汀钙片治疗的疗效确切。
Objective: To investigate the clinical effect of amlodipine atorvastatin calcium tablet on Patients with hypertension with coronary heart disease( CHD). Methods: A total of 92 cases of hypertension patients with coronary heart disease( CHD) were were divided into control group and experimental group. The control group treated with nifedipine zyban,experimental group treated with solid amlodipine atorvastatin calcium tablet. Comaring indexes of blood pressure,total cholesterol and triglyceride. Results: The systolic and diastolic blood pressure of two groups before treatment showed no statistical significance( P > 0. 05). After treatment,systolic and diastolic blood pressure of experimental group were significantly lower than control group( P < 0. 05). The experimental group total effective rate was 95. 65%; the control group total effective rate was 82. 61%( P < 0. 05); TC,TG,LDLL,HDL-L index of experimental group were lower than that of control group significantly( P < 0. 05).Conclusion: Amlodipine atorvastatin calcium tablet is effective for patients with hypertension with coronary heart disease.

关键词(KeyWords): 高血压;冠心病;氨氯地平;阿托伐他汀;疗效
hypertension;coronary heart disease;amlodipine;atorvastatin;curative effect

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作者(Author): 陈鼎;张贤春;陈漠水;
CHEN Ding;ZHANG Xianchun;CHEN Moshui;General Department,Branch Hospital of Haikou People's Hospital;Department of Cardiology,Haikou People's Hospital;

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