贵州医科大学学报

1993, (02) 90-93

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用评分法再评价磷酸喹哌治疗煤矽肺的疗效
Reassessing the Result of a Treatment for Anthraco-silicosis Patients by Piperaquini Phosphas with a Scoring Method of Chest X-ray Film

谢亚雄;黄建权;哈宽庭;
Xie Yaxiong, et al Department of Occupational Health

摘要(Abstract):

对1976年用磷酸喹哌试验治疗过的35名煤矽肺患者重新设置对照,并用新的尘肺胸片记录评分法重新评价该药物的疗效,结果表明磷酸喹哌对煤矽肺并无明显疗效(包括近期、中期和远期疗效)。此评分法是根据胸片尘肺表现的严重程度,赋予胸片适当的评分,其理论基础是ILO尘肺胸片国际分类法,并根据我国尘肺诊断标准的规定来决定各期尘肺的评分范围。用该方法来评价药物对尘肺的疗效,可使分析结果更加精确、客观和相对定量化。
The result of a trial treatment for 35 anthraco-silicosis patients by piperaquini phosphas in 1976 was reassessed. In 1976, it was regarded as effective to certain degree on anthraco-silicosis by the drug, and the effectiveness was mainly shown by amelioration of X-ray manifestation, clinical symptoms, and biochemical tests. But no necessary controls were set, and no quantitative index was used for the analysis of chest X-ray films. In 1987, control group of patients of anthraco- silicosis matched in age, worklif and severity with the above-mentioned 35 patients were selected and observed. A new scoring method of chest X-ray film was used in assessing the effective ness of the drug.In the scoring method, which is based on the ILO Classification of Chest Roentgenograph of Pneumoconiosis and the Roentgenodiagnostic Criteria of Pneumoconiosis of this country, a proper score is given to a film according its severity of the radiographic changes of pneumoconiosis. The result of analysis could not show obvious therapeutic effectiveness of piperaquini phosphas on anthraco-silicosis, including the effectiveness in short-term, medium-term and long-term.

关键词(KeyWords): 磷酸喹哌;治疗学;肺煤末矽末沉着病;评分
piperaquini phosphas;therapeutics;anthraco-silicosis;score

Abstract:

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作者(Author): 谢亚雄;黄建权;哈宽庭;
Xie Yaxiong, et al Department of Occupational Health

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DOI: 10.19367/j.cnki.1000-2707.1993.02.003

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