贵州医科大学学报

2014, v.39;No.171(06) 848-850

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脑出血患者脑利钠肽前体和超敏肌钙蛋白的水平及意义
Levels of Brain Natriuretic Peptide Precursor and High Sensitive Troponin of Intracerebral Hemorrhage Patients and Its Clinical Significance

杨会;宋安军;刘兴德;
YANG Hui;SONG Anjun;LIU Xingde;Department of Cardiology,Affiliated Hospital of Guiyang Medical University;Department of Emergency Neurology,Affiliated Hospital of Guiyang Medical University;

摘要(Abstract):

目的:探讨脑利钠肽前体(NT-pro BNP)和超敏肌钙蛋白T(c Tn T)在急性脑出血患者血浆中的水平。方法:高血压脑出血患者60例,根据病历资料及治疗结果分为康复组和死亡组,用电化学发光法检测2组患者入院第1天时血浆NT-pro BNP和c Tn T水平,同时观察康复组患者入院后第7天和第14天时血浆NT-pro BNP和c Tn T水平。结果:与康复组比较,入院第1天时死亡组患者NT-pro BNP和c Tn T均显著升高,差异有统计学意义(P<0.05);康复组患者脑出血第7天时,NT-pro BNP和c Tn T显著高于第1天和第14天,差异有统计学意义(P<0.05)。结论:急性脑出血预后与发病时患者血浆NT-pro BNP和c Tn T水平有关,NT-pro BNP和c Tn T水平在发病后第7天最高。
Objective: To investigate plasma levels and its clinical significance of brain natriuretic peptide precursor( NT-pro BNP) and high sensitive cardiac troponin T( c Tn T) in intracerebral hemorrhage patients. Methods: According to medical reocrds and treatment results,60 patients with hypertensive cerebral hemorrhage were divided into rehabilitation group and death group. NT-pro BNP and c Tn T levels of death group on the first day after admission and rehabilitation group on the 1st,7thand14 thdays after admission were tested by electrochemiluminescence immunoassay. Results: Compared with rehabilitation group,NT-pro BNP and c Tn T levles of death group on the first day after admission were increased significantly( P < 0. 05). NT-pro BNP and c Tn T levels of patients in rehabilitation group on the seventh day were higher than those on the first day and the fourteenth day( P < 0. 05).Conclusions: Prognosis of patients with acute cerebral hemorrhage is correlated with NT-pro BNP and c Tn T levels,which reach the highest on the seventh day after disease incidence.

关键词(KeyWords): 脑出血;高血压;脑利钠肽前体;超敏肌钙蛋白T;化学发光
cerebral hemorrhage;hypertension;brain natriuretic peptide precursor;high sensitive cardiac troponin T;electrochemiluminescence

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作者(Author): 杨会;宋安军;刘兴德;
YANG Hui;SONG Anjun;LIU Xingde;Department of Cardiology,Affiliated Hospital of Guiyang Medical University;Department of Emergency Neurology,Affiliated Hospital of Guiyang Medical University;

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