贵州医科大学学报

2012, v.37;No.158(05) 520-522

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大肠癌临床病理特征及血液微转移与预后的关系
Relationship of Clinicopathological Features and Blood Micrometastasis to Prognosis of Patients with Colorectal Cancer

杨晓武;张汝一;甄运寰;李国胜;程海玉;龚慧;颜登国;
YANG Xiaowu,ZHANG Ruyi,ZHEN Yunhuan,LI Guosheng,CHENG Haiyu,GONG Hui,YAN Dengguo(Department of Surgery,the Affiliated Hospital of Guiyang Medical College,Guiyang 550004,Guizhou,China)

摘要(Abstract):

目的:探讨大肠癌的临床病理学特征及血液微转移与预后的关系。方法:分析61例手术和病理确诊、且随访资料完整的大肠癌患者的临床资料及血液微转移情况,并与生存率进行单因素和多因素Cox回归分析,分析影响大肠癌预后的因素。结果:单因素分析结果显示,肿瘤直径、病理类型、TNM分期、治疗方法、外周血及门静脉血癌细胞检测与预后相关;多因素回归分析显示,肿瘤直径及TNM分期是影响大肠癌患者术后生存的独立因素。结论:大肠癌患者的预后与肿瘤的多种临床病理因素相关。
Objective: To explore the relationship of clinicopathological features and micrometastasis to prognosis of colorectal cancer.Methods: Clinical data and micrometastasis condition of 61 patients with surgically and pathologically confirmed colorectal cancer who had complete follow-up data were statistically analyzed.Univariate and multivariate analysis were carried out to determine factors affecting prognosis of colorectal cancer.Results: Univarite analysis showed that the diameter of the tumors,pathological type,TNM staging,therapeutic methods,detectable cancer cells in peripheral blood and portal vein were related to the prognosis of colorectal cancer.Multivariate analysis showed that diameter of the tumors and TNM staging were independent factors affecting postoperative survival time.Conclusions: The prognosis of colorectal cancer is related to multiple clinical pathological factors.

关键词(KeyWords): 大肠;癌;病理学;肿瘤转移;门静脉;预后
intestine,large;carcinoma;pathology;neoplasm metastasis;portal vein;prognosis

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作者(Author): 杨晓武;张汝一;甄运寰;李国胜;程海玉;龚慧;颜登国;
YANG Xiaowu,ZHANG Ruyi,ZHEN Yunhuan,LI Guosheng,CHENG Haiyu,GONG Hui,YAN Dengguo(Department of Surgery,the Affiliated Hospital of Guiyang Medical College,Guiyang 550004,Guizhou,China)

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DOI: 10.19367/j.cnki.1000-2707.2012.05.019

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