贵州医科大学学报

2015, v.40;No.173(02) 201-204

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氨氯地平联合阿托伐他汀钙片对高血压合并冠心病的治疗效果
The Treatment Effect of Amlodipine Combined Atorvastatin Calcium Tablets on Hypertension with Coronary Heart Disease

杨漫沩;何晓玲;刘欣;刘少文;
HUANG Manwei;HE Xiaoling;LIU Xin;LIU Shaowen;The Hospital of Chinese Geology University;

摘要(Abstract):

目的:探讨氨氯地平联合阿托伐他汀钙片对高血压合并冠心病的临床治疗效果。方法:92例高血压合并冠心病患者,按照入院时间均分为对照组和观察组,对照组采取阿托伐他汀治疗,观察组则采用氨氯地平联合阿伐他汀治疗;比较治疗前和治疗8周后两组患者血压、血脂、心电图改变情况、硝酸甘油片的使用量和心绞痛改善情况。结果:治疗8周后,观察组血压和血脂水平明显低于对照组,差异均有统计学意义(P<0.05);观察组的降压、降血脂治疗有效率,心绞痛、心电图改变情况同对照组相比差异有统计学意义(P<0.05);观察组病例硝酸甘油片的使用量大大减少,总有效率与对照组相比差异有统计学意义(P<0.05)。结论:氨氯地平联合阿托伐他汀钙片能有效地控制和改善高血压合并冠心病患者心率、血压等情况,治疗效果明显。
Objective: To study the curative effect of amlodipine combined with atorvastatin calcium tablets on hypertension with coronary heart disease. Methods: Ninety-two hypertension patients with coronary heart disease were were divided into control group and observation group. The observation group was treated with atorvastatin calcium tablets; Treatment group was given amlodipine combined with atorvastatin calcium tablets. Blood pressure,blood lipid,and electrocardiogram changes,the usage of nitroglycerin tablets and improvement of angina pectoris were compared between the two groups before and 8 weeks after the treatment. Results: After 8 weeks of treatment,the blood pressure and blood lipid levels of observation group were significantly lower than those of control group,the difference was statistically significant( P < 0. 05). The curative efficiency of reducing blood pressure and blood lipid,the improvement of angina pectoris and electrocardiogram in observation group were more remarkable than those in control group,differences were statistically significant( P < 0. 05). Compared with control group,nitroglycerin consumption in observation group greatly reduced,differences were also statistically significant( P < 0. 05). Conclusions: Amlodipine combine with atorvastatin calcium tablets can effectively control and improve heart rate,blood pressure of patients with hypertension and coronary heart disease,treatment effect is obvious.

关键词(KeyWords): 氨氯地平;阿托伐他钙片;高血压;冠心病
amlodipine;atorvastatin calcium tablets;hypertension;coronary heart disease

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作者(Author): 杨漫沩;何晓玲;刘欣;刘少文;
HUANG Manwei;HE Xiaoling;LIU Xin;LIU Shaowen;The Hospital of Chinese Geology University;

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