贵州医科大学学报

2018, v.43;No.216(09) 1101-1104

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PCT、Hs-CRP水平联合PCIS评分在儿童脓毒症中的诊断价值
Diagnostic Value of PCT and Hs-CRP Levels Combined with PCIS Score in Children with Sepsis

于航;朝鲁门其其格;
YU Hang;CHAO Lumenqiqige;Children's Intensive Care Unit,Affiliated Hospital of Inner Mongolia Medical University;

摘要(Abstract):

目的:探讨降钙素原(PCT)、超敏C蛋白(Hs-CRP)水平及小儿危重病例评分法(PCIS)对儿童脓毒症的诊断价值。方法:选择59例脓毒症患儿(脓毒症组)及同期住院的68例非脓毒症患儿(非脓毒症组)为研究对象,两组患儿在入院24 h内进行PCIS评分;脓毒症组患儿根据PCIS评分分为非危重组(> 80分)、危重组(80~71分)和极危重组(≤70分),检测各组患儿血清PCT、Hs-CRP水平,比较脓毒症和非脓毒症患儿、脓毒症各组患儿血清PCT、Hs-CRP水平,并分析PCT、Hs-CRP与PCIS的相关性。结果:脓毒症组患儿血清PCT、HsCRP水平高于非脓毒症组,PCIS评分低于非脓毒症组(P <0. 05);脓毒症危重组和极危重组患儿血清PCT、HsCRP水平高于非危重组,极危重组患儿血清PCT、Hs-CRP水平高于危重组(P <0. 05);脓毒症组患儿PCIS评分与血清PCT、Hs-CRP水平均呈负相关(r分别为-0. 527、-0. 351,P <0. 05)。结论:PCT、Hs-CRP联合PCIS对儿童脓毒症的诊断和病情判断中具有一定的价值。
Objective: To explore the diagnostic value of PCT,Hs-CRP level and PCIS score in children with sepsis. Methods: 59 children with sepsis( sepsis group) and 68 children with non-sepsis( non-sepsis group) who were hospitalized at the same time were selected as the study subjects. The PCIS scores of the two groups were evaluated within 24 hours after admission,and according to the PCIS scores,the sepsis group were divided into three sub-groups: non-critical group( scores above80),critical group( scores between 80 and 71) and extremely critical group( scores below 70). Then the serum PCT and Hs-CRP levels were measured,the serum PCT,Hs-CRP levels of sepsis and nonsepsis children as well as the three sub-groups of the sepsis group were compared,and the correlation between PCT,Hs CRP and PCIS was analyzed. Results: The levels of serum PCT and Hs-CRP in sepsis group were higher than those in non-sepsis group,and PCIS score was lower than that in non-sepsis group( P < 0. 05). The levels of serum PCT and Hs-CRP were higher in the critical and extremely critical groups than in the non-critical group,and the levels of serum PCT and Hs-CRP in the extremely critical group were higher than those in critical group( P < 0. 05). There was a negative correlation between PCIS score and serum PCT,Hs-CRP level in sepsis group( r =-0. 527 and-0. 351 respectively,P < 0. 05). Conclusion: PCT and Hs-CRP combined with PCIS have certain value in the diagnosisof sepsis in children.

关键词(KeyWords): 儿童脓毒症;急性期;降钙素原;超敏C反应蛋白;PCIS评分;诊断价值
sepsis in children;acute stage;procalcitonin;high sensitive C reaction protein;PCIS score;diagnostic value

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作者(Author): 于航;朝鲁门其其格;
YU Hang;CHAO Lumenqiqige;Children's Intensive Care Unit,Affiliated Hospital of Inner Mongolia Medical University;

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