贵州医科大学学报

1996, (03)

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219例不同疾病D-二聚体的检测
Detection of D-Dimer in Serum of 219 Patients

谭玉洁,黄铁生
Tan Yujie, et al(Department of Clinical Biochemistry, Guigang Medical College)

摘要(Abstract):

应用Latex法检测了219例不同疾病患者血浆或血清D-二聚体的浓度,结果表明血栓性疾病患者该浓度显著升高,且急性期与缓解期有显著性差异(P<0.01)。在肝脏疾病患者D-二聚体升高的程度与肝脏损害的程度有关,尤其在区分肝硬变的代偿期和失代偿期方面有显著性意义(P<0.001)。结果还表明D-二聚体在恶性肿瘤、肾病、肺炎、妊高征、白血病等多种疾病以及手术后均有升高,提示存在多种疾病时,机体可能出现血栓形成倾向。
Is the thesis, 219 clinical patients serum were detected in using D-dimer latex. The patients detected with D-dimer had been diagnosed in different disease. It shows that those patients from thrombotic disease had serum D-dimer concentration at a higher level, and there is an obvious difference between the consistency in the acute stage and remisson stage (P<0.001), D-dimer consisteney is a important laboratory diagnosic index. Further more, there ls an important point in observing the course of treatment and evaluation of therapeutic efficiency for thrombolytic therapy. In the study of hepatology, the consistency of D-dimer was correlated with the level of hepar damage. It is especially significant for differentiating the compensatory phase of cirrhosis and the decompensation phase (P<0.001). The results indicate D-dimer consistency becomes higher in malignant, tumour, nephrosis, pneumonia,hypertension of pregnacy, leukemia and many other diseases,as well as after surgical operation.

关键词(KeyWords): D-二聚体,血栓栓塞,肝疾病
D-dimer; thromboembolism; liver diseases

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作者(Author): 谭玉洁,黄铁生
Tan Yujie, et al(Department of Clinical Biochemistry, Guigang Medical College)

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