影响癫痫患者智力的多因素研究Correlative Study on the Influence Factors of Intelligence in Adult Epileptic Patients
王丽娟;卢亮;
Wang Lijuan, Lu Iiang Guizhou Geriatrics Institute
摘要(Abstract)：
本文采用WAIS—RC对101例成人癫痫患者与84例正常成人进行智能对照研究。癫痫患者言语智商、操作智商、总智商、言语理解因子、知觉组织因子、记忆不分心因子及11项分测验得分均明显低于对照组,其中智能缺陷占45.55％。文中还采用多元回归分析探讨了可能影响癫痫患者智能的因素。
The WAIS-RC performence was investigated in 101 adult epileptic patients with seizures and 84 normal controls, enrolled in a casecontrol study. In the study group, VlQ, PIQ, FIQ, VC, PO, MF and 11 subtests scares were significantly lower than those in the control group. The proportion of intelligence deficiency (IQ<70) in the study group was 45.55%. Summarized according to the multiple regression analysis,the factors affecting the 17 intelligence indices of the epileptic patients were multiple, including disease factors and non-disease factors. They were arranged in the affected degrees from great to small:degrees of education,occupation,type of seizures, number of antiepileptic medications taken, EEG changes, sex, duration between the last seizures and the performence of WAIS-RC test, duration of seizures, the time of seizures,age at onset of seizures,frequency of seizures and years of antiepileptic medications taken.
关键词(KeyWords)： 癫痫;智力;回归分析
epilepsy;intelligence;regression analysis
基金项目(Foundation):
作者(Author): 王丽娟;卢亮;
Wang Lijuan, Lu Iiang Guizhou Geriatrics Institute
Email:
参考文献(References)：
- 1 Commision on classification and terminology of the international league against epilepsy-seizures. Epilepsia, 1981, 22: 489-501
- 2 龚耀先.WAIS-RC与原量表(WAIS和WAIS-R)因素分析的比较研究.心理学报,1987,19:70
- 3 Lawson J S, et al. A laterality index of cognitive impairment after hemispheric damage: A measure derived from a principal components analysis of the wechsler adult intelligence scale. J Consult Clin Psycho], 1983, 51 (6) : 832-840
- 4 Klesges R C, et al. Predicting adult prenorbid functioning levels another look. The Int J Clin Neuropsychol,1934, 7: 13
- 5 Karzmark P, et al. Use of damograpaic variable to prelict fullscale IQ: A replication and extension, J Clin Exp Neurcpsychol, 1985, 7: 412-420
- 6 Giordani B, et al. Intelligence test performance of patients with partial and generalized.Epllepsia, 1985, 26 (1) : 37-42．
- 7 Car B Dodrill. Correlates of generalized tonic-clonic seizure with in elleotual neuropsychological, emotional and social function in patients witlh epilepsy. Epilepsia, 1986, 27(4) : 399-411
- 8 Thompson PJ, et al. Amtin ulsant drugs and congnitive functions. Epilepsia, 1982, 23: 531-544
- 9 周树舜.抗癫痫药物对高级神经功能的毒副作用.国外医学 神经病学分
- 10 Nie nann H. Cognitive development in epilepsy. The relative influence of epileptic activity and of brain danage. Eur Arch Psychiatry Neurol Sci,1985, 234(6) : 399-403
- 11 Lesser RP, et al. Mental deterio ration in epilepsy. Epilepsia, 1986, 27 suppl 2(4) : 105-123
- 12 沈渔邨.精神病学.第二版.北京:人民卫生出版社,1988,584～595
文章评论(Comment)：
|
||||||||||||||||||
|
||||||||||||||||||