贵州医科大学学报

1995, (02)

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早期诊断的地方性克汀病随访观察
A Follow up Survey of Endemic Cretinism Diagnosed in Infancy

曾国珩,周崇科,徐文军,柯永勤,周石,陆黎,郑勇,李鹏
Zeng Guoheng,et al (Department of psychiatry,Guiyang Medical College)

摘要(Abstract):

1979年用精神神经检查、甲状腺功能检查和骨龄判断,检查地方性克汀病(地克病)病区2岁内儿童103人,检出精神神经征阳性儿童25人,甲状腺功能低下(甲低)26人,骨龄延迟27人。1992年进行随访并作智力测验,结果:诊断为地克病和业临床地克病(亚克汀)的在精神神经征阳性25人中有18人,诊断一致率为72.0%;在甲低26人中有16人,一致率为61.5%;在骨龄延迟25人中有16人,一致率64.0%。表明3种方法对早期诊断地克病都有一定价值,尤以精神神经检查简便易行。
The authors scrutinized 103 children under 2 years of age in an endemic area using psychoneurological examinations, serum T4 and TSH determination and roentgenological examination of bone age to study the early diagnosis of endemic cretinism in 1979.25 children were picked out with psychoneurological abnormalities,26 with hypothyroidism and 27 with delay bone age.A 13 Years follow up survey and intelligence tests of those children were carried out in 1992. The results were as follows:18 out of 25 follow up children with psychoneuorological abnormalities were diagnosed as endemic cretinism and subclinical cretinism.16 out of 26 children with hypothyroidism and 16 out of 25 children with delay bone age were diagnosed as endemic cretinism and subclinical cretinism.The rates of accordance with their final diagnosis were 72.0%,61.5%and 64.0%, respectively. It suggests that those 3 methods for early diagnosis of endemic cretinism are valuable,especially the psychoneurological examination.

关键词(KeyWords): 克汀病,诊断,随访研究
cretinism; diagnosis; follow up studies

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作者(Author): 曾国珩,周崇科,徐文军,柯永勤,周石,陆黎,郑勇,李鹏
Zeng Guoheng,et al (Department of psychiatry,Guiyang Medical College)

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